Federal allocations of monoclonal antibody treatments paused due to Omicron resistance

Staff Report
Registered nurse Salah Hadwan infuses patient Rebecca Ivey, 54, with monoclonal antibody treatment at Wayne Health Detroit Mack Health Center in Detroit on Dec. 10.

The Louisiana Department of Health is pausing administration of monoclonal antibody treatments at LDH-run treatment sites in response to a federal decision to cease state allocations.

LDH sites previously offered two mAb treatments: REGEN-COV and bamlanivimab and etesevimab administered together. However, recent data demonstrate that these two monoclonal antibodies are not effective against the Omicron variant, which is now the dominant variant circulating in the U.S. 

As a result, the federal government paused further allocations of these monoclonal antibodies pending updated data from the Centers for Disease Control and Prevention.

Louisiana has received a limited supply - 228 doses - of another monoclonal antibody treatment, sotrovimab, which appears to remain effective against the Omicron variant for prevention of severe disease. Additional allocations of sotrovimab are expected in January.

Limited doses of sotrovimab have been distributed to the following select hospitals across the state. However, the treatment will be in scarce supply until new deliveries arrive. As supply becomes more widely available, LDH will be ready to reopen sites when there a sufficient allocation for hospitals and community sites.

The following hospitals are expected to receive shipments of sotrovima:

  • North Oaks Medical Center, 15790 Paul Vega MD Drive, Hammond
  • Ochsner Medical Center, 1514 Jefferson Drive, New Orleans
  • Our Lady of the Lake Regional Medical Center, 5000 Hennessy Blvd., Baton Rouge
  • St. Francis Medical Center, 309 Jackson St., Monroe
  • University Medical Center, 2000 Canal St., New Orleans
  • Lake Charles Memorial Hospital, 1701 Oak Park Blvd., Lake Charles

Monoclonal antibody treatments are a pharmaceutical intervention used to treat people who are infected with the virus that causes COVID-19. Monoclonal antibody treatment can prevent severe illness, hospitalization, and death in high-risk patients.

Those with questions about whether monoclonal antibodies are an appropriate treatment for them should contact their provider. Those experiencing symptoms but do not have a provider can call the Combat COVID Monoclonal Antibodies Call Center at 1-877-332-6585.